Zizheng Dong Selected Research

Eukaryotic Initiation Factor-3

1/2022	Translation initiation factor eIF3a regulates glucose metabolism and cell proliferation via promoting small GTPase Rheb synthesis and AMPK activation.
1/2017	eIF3 Regulation of Protein Synthesis, Tumorigenesis, and Therapeutic Response.
9/2013	Spectrin domain of eukaryotic initiation factor 3a is the docking site for formation of the a:b:i:g subcomplex.
9/2006	Initiation factor eIF3 and regulation of mRNA translation, cell growth, and cancer.
5/2004	Role of eIF3 p170 in controlling synthesis of ribonucleotide reductase M2 and cell growth.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Zizheng Dong Research Topics

Disease

22	Neoplasms (Cancer) 01/2022 - 08/2003
3	Carcinogenesis 01/2021 - 09/2013
2	Breast Neoplasms (Breast Cancer) 01/2021 - 11/2017
2	Pancreatic Neoplasms (Pancreatic Cancer) 11/2014 - 11/2010
1	Prostatic Neoplasms (Prostate Cancer) 01/2022
1	Triple Negative Breast Neoplasms 11/2021
1	Adenocarcinoma 04/2016
1	Nasopharyngeal Carcinoma 10/2013
1	Fibrosis (Cirrhosis) 11/2012
1	Ureteral Obstruction 11/2012
1	Lymphatic Metastasis 11/2010
1	Testicular Neoplasms (Testicular Cancer) 11/2010
1	Virus Diseases (Viral Diseases) 01/2005
1	Lung Neoplasms (Lung Cancer) 05/2004
1	Acute Erythroblastic Leukemia (Erythroleukemia) 11/2003

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2010
5	Eukaryotic Initiation Factor-3IBA 01/2022 - 05/2004
5	Pharmaceutical PreparationsIBA 01/2021 - 05/2009
3	SurvivinIBA 01/2022 - 01/2016
3	Fatty Acid Synthases (Fatty Acid Synthase)IBA 11/2021 - 11/2016
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 05/2014
3	Messenger RNA (mRNA)IBA 11/2010 - 11/2003
2	Inhibitor of Apoptosis ProteinsIBA 01/2022 - 01/2020
2	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 10/2013
2	ATP-Binding Cassette Transporters (ABC Transporters)IBA 12/2019 - 05/2007
2	Adenosine Triphosphate (ATP)IBA 12/2019 - 03/2007
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2018 - 05/2014
2	Gemcitabine FDA Link 04/2016 - 11/2014
2	Peptide Initiation Factors (Initiation Factor)IBA 09/2013 - 09/2006
1	ProdrugsIBA 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	OxadiazolesIBA 01/2022
1	Docetaxel (Taxotere)FDA Link 01/2022
1	HydrazonesIBA 01/2022
1	Prokaryotic Initiation Factor-3IBA 01/2022
1	Proton Pump InhibitorsIBA 01/2021
1	AlkaloidsIBA 01/2018
1	bisindolylmaleimideIBA 01/2018
1	Protein Kinase CIBA 01/2018
1	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2017
1	Hyaluronic Acid (Hyaluronan)IBA 11/2017
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2017
1	EnzymesIBA 11/2016
1	LipidsIBA 11/2016
1	Oncogene Proteins (Oncogene Protein)IBA 01/2016
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2016
1	Antineoplastic Agents (Antineoplastics)IBA 01/2016
1	Cytarabine (Cytosar-U)FDA LinkGeneric 11/2014
1	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 11/2014
1	Aspartate-Ammonia Ligase (Asparagine Synthetase)IBA 10/2013
1	matrix metalloproteinase 19IBA 10/2013
1	PlatinumIBA 10/2013
1	salicylhydroxamic acid (SHAM)IBA 11/2012
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 11/2012
1	Interleukin-18 (Interleukin 18)IBA 11/2012
1	Membrane Transport Proteins (Biological Pump)IBA 03/2007
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 03/2007
1	multidrug resistance-associated protein 1IBA 03/2007
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 08/2003
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 08/2003

Therapy/Procedure

5	Drug Therapy (Chemotherapy) 12/2019 - 03/2007
4	Therapeutics 01/2017 - 05/2009
1	Radiotherapy 01/2017
1	Chemoradiotherapy 10/2013